Researchers identify metastasis driver in BRAF inhibitor resistant melanoma

Targeted therapy with BRAF-MEK inhibitors is an effective treatment for patients with advanced melanoma that cannot be surgically removed or has spread to other areas of the body. However, many patients become resistant to the therapy, and this can often lead to further metastasis. Moffitt Cancer Center researchers who helped develop this type of combination […]

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Finding cortisone alternatives with fewer side effects

Many people use cortisone of a regular basis. It is used for treating rheumatism, asthma, multiple sclerosis, or even COVID-19. Steroidal medication such as cortisone is highly effective but also possesses severe side effects. Henriette Uhlenhaut, professor at Technical University of Munich (TUM), and her team are examining the beneficial effects of cortisone in order […]

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Subtypes and developmental pathways of innate T cells identified

There are memory cells that remember previously encountered pathogens and help to react quickly and strongly when exposed to them again. The developmental process of strong immune cells that make these memory cells in advance without having to encounter the pathogens have been discovered. Understanding the developmental process of these cells, which are responsible for […]

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Predictive placentas: Using artificial intelligence to protect mothers’ future pregnancies

After a baby is born, doctors sometimes examine the placenta—the organ that links the mother to the baby—for features that indicate health risks in any future pregnancies. Unfortunately, this is a time-consuming process that must be performed by a specialist, so most placentas go unexamined after the birth. A team of researchers from Carnegie Mellon […]

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Doctors offer practical advice on reaching peak performance during surgical training

Studies show that athletes and musicians achieve peak performance not only by constant practice but also by setting specific goals, engaging with strong mentors and cultivating the attributes of perseverance, stoicism and grit. Could incorporating these principles into the training of surgeons improve their residency experience and make them better doctors? Philip Louie, MD, who […]

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Partnership leverages evidence-based practices to improve long-term care quality

A study published in the Journal of the Medical Directors Association demonstrated that a partnership between long-term care organizations in two countries working in collaboration with researchers and national health care organizations can generate changes that improve quality of care for residents. Authors of “The Seniors Quality Leap Initiative: An International Collaborative to Improve Quality […]

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